I recently rebuilt my mac and I was curious where the Image Capture Driver came from – it comes from apple – Image Capture worked with the GT-S50 before I ever installed the drivers from Epson.

My workflow is basically to use Acrobat to scan via Twian (Acrobat on the mac doesn’t support Image Capture nor ISIS drivers) which has worked out pretty well.

The Image capture app from apple can also create PDF’s but they aren’t searchable and they are quite a bit (5-10x) larger than the PDF’s Acrobat creates.

I think the Epson is a solid scanner for the money (Cheaper than the Canon and Fujitsu)
I am still curious about the Canon, as it was rated faster and still has twian drivers.
Unfortunately for Canon (and me) there wasn’t anywhere I could go see/get one.

Other than twain, I don’t think you can go wrong with ScanSnap- people seem to love them, and it comes with Acrobat, which is a must have. It is disappointing that there is no twain driver, which means there might be scenarios in the future where you have to scan to a Tiff file then import it into another program- that said, 99.5% of what we scan we likely want in PDF format, and I think the ScanSnap has that down, plus although late, I think Fujitsu’s been pretty good about supporting older product with drivers.

I’ve been thinking of buying the GT-S50 over the ScanSnap, hoping the TWAIN drivers would help me avoid “lock-in”. After all these decades nobody has gotten scanner software right! Sounds like Fujitsu has come close yet when OS-X 10.7 comes out, we’ll all be stuck again. And when 10.9 is around, who knows if they’ll even support it anymore? Argh!